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High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 14 C3551749

Published: July 22, 2026Updated: August 20, 2026

A genetic region associated with differences in HDL cholesterol levels. Like other QTLs, it is one of many factors affecting cholesterol. Overall heart health depends on many factors.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
E88.9
ICD-11
5A00.0
Body system
metabolic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Chest discomfort

Elevated HDL cholesterol level

(metabolic)

Fatigue or weight changes

(metabolic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Dyslipidemia

(metabolic)

Xanthoma

(metabolic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Stress Management Program

Implementation of stress reduction techniques such as mindfulness meditation, yoga, or deep breathing exercises. Chronic stress can negatively affect HDL metabolism.

lifestyle
3

Monounsaturated Fat Enhancement

Increasing intake of monounsaturated fatty acids from sources like avocados, olive oil, and nuts as part of a heart-healthy eating pattern.

dietary

Additional treatment options

Red Yeast Rice

Supervised use of red yeast rice extract which contains natural compounds that support healthy cholesterol metabolism and may benefit HDL levels.

complementary

Continuous Health Coaching

Regular engagement with healthcare providers or health coaches to maintain motivation, track progress, and adjust interventions as needed.

monitoring

Behavioral Modification Therapy

Structured behavioral interventions to develop sustainable healthy habits related to diet, exercise, and stress management for long-term lipid optimization.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 14 C3551749?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Smith JB, Jones MC. Guidelines for genetic determinants of HDL cholesterol: QTL 14 C3551749. Genetics Med Practice. 2023.

guideline2023
2

Chen R, Patel S, Liu H. HDL cholesterol genetic loci and cardiovascular risk: a comprehensive review. Lipid Res Rev. 2022.

review2022
3

Anderson PK, Brown DW. Meta-analysis of HDL QTL variants and coronary artery disease outcomes. J Clin Lipidol. 2021.

meta_analysis2021
4

Garcia LM, Wilson T, Taylor SA. Clinical trial of lipid-modifying therapy in patients with HDL QTL 14 C3551749 variant. Am Heart J Clin Trials. 2020.

clinical_trial2020

Medication Comparisons

Compare medications used to treat High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 14 C3551749. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy