Holoprosencephaly 9 C1835819
Holoprosencephaly 9 is a severe congenital brain abnormality where the forebrain does not properly divide into two lobes. This genetic condition occurs during early pregnancy. Management involves multidisciplinary care addressing neurological and associated features.
Key facts at a glance
- ICD-10
- Q04.2
- ICD-11
- LA00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Epilepsy
Craniofacial dysmorphism
(neurologic)Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Optic nerve hypoplasia
(neurologic)Thyroid dysfunction
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Neurosurgical intervention for hydrocephalus
Surgical management of hydrocephalus through shunt placement or alternative techniques appropriate for the specific anatomical presentation.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Serial neuroimaging and clinical assessment
Regular MRI or CT imaging combined with clinical neurological examinations to monitor brain development and detect complications.
Additional treatment options
Skull circumference and growth monitoring
Regular measurement of head circumference and developmental milestones to assess progression and identify need for intervention.
procedureNutritional support and management
Dietary planning and supplementation to address feeding difficulties, ensure adequate caloric intake, and manage any associated metabolic issues.
dietaryFamily-centered psychosocial intervention
Psychological support services for families addressing grief, adjustment, and coping with chronic neurological condition including sibling support.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Holoprosencephaly 9 C1835819?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Holoprosencephaly 9 C1835819. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy