Hypercalcemia Infantile 2 C4310473
A severe metabolic disorder causing extremely high calcium levels in infants, which can damage organs and be life-threatening. Careful medical management is essential to normalize calcium and prevent complications.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe hypercalcemia
Fatigue or weight changes
(metabolic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Hypercalciuria
(renal)Polyuria
(endocrine)Failure to thrive
(growth)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
IV Hydration and Calciuresis
Aggressive intravenous fluid administration with saline to enhance renal calcium excretion and reduce serum calcium levels in infants with severe hypercalcemia.
Low Calcium Formula Diet
Specialized infant formula with reduced calcium content to limit calcium intake while maintaining adequate nutrition for growth and development.
Additional treatment options
Bisphosphonate Therapy
Intravenous bisphosphonates such as pamidronate may be used for severe hypercalcemia unresponsive to other measures.
medicationCalcitonin Therapy
Synthetic calcitonin to suppress bone resorption and lower serum calcium levels when standard measures are insufficient.
medicationCardiac and Renal Monitoring
Continuous monitoring for cardiac arrhythmias and renal complications from hypercalcemia including nephrocalcinosis assessment.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Hypercalcemia Infantile 2 C4310473?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy