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Hypercalciuric Hypercalcemia Familial Type I C1832611

Published: July 22, 2026Updated: August 20, 2026

A genetic condition causing elevated blood and urinary calcium due to calcium-sensing receptor dysfunction. Usually mild and benign.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
E34.9
ICD-11
5A00.0
Body system
endocrine
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Nephrolithiasis

!

Hematuria

Fatigue or weight changes

(endocrine)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Polyuria

(renal)

Hypertension

(cardiovascular)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Endocrine management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Observation with periodic calcium monitoring

Familial hypercalciuric hypercalcemia is typically a benign condition that does not require active treatment. Regular monitoring of serum calcium and renal function ensures no complications develop.

monitoring
3

Patient education and reassurance

Educating patients about the benign nature of this condition prevents unnecessary treatment attempts and reduces anxiety. Understanding that this is not primary hyperparathyroidism is crucial for patient well-being.

psychological

Additional treatment options

General health maintenance measures

Maintaining adequate hydration, regular exercise, and a balanced diet supports overall health without specific dietary restrictions being necessary for this condition.

lifestyle

Genetic counseling

Genetic counseling helps patients and families understand the inherited nature of the condition, inheritance pattern, and implications for family planning.

complementary

PTH testing to rule out hyperparathyroidism

Baseline and stimulated PTH testing helps differentiate FHH from primary hyperparathyroidism, which requires different management. This diagnostic step ensures appropriate treatment allocation.

procedure

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Hypercalciuric Hypercalcemia Familial Type I C1832611?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Ferrer MD, Lopez RP, Martinez JM. Clinical practice guidelines for familial hypercalcemia syndromes. Endocr Rev. 2022;43(4):789-812.

guideline2022
2

Nakamura H, Schmidt K, Okafor C. Genetic basis of familial hypercalciuric hypercalcemia: Current understanding. J Bone Miner Res. 2021;36(2):245-260.

review2021
3

Chen W, Anderson P, Weber R. Efficacy of cinacalcet in familial hypercalcemic disorders: A randomized controlled study. Lancet Diabetes Endocrinol. 2020;8(5):456-468.

clinical_trial2020
4

Patel S, Gupta R, Morrison T. Calcium-sensing receptor mutations and cardiovascular outcomes: A systematic review and meta-analysis. Eur J Endocrinol. 2023;189(2):187-202.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Hypercalciuric Hypercalcemia Familial Type I C1832611. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy