Hypercholesterolemia Autosomal Dominant Type B C1704417
A hereditary disorder causing very high cholesterol levels that can be passed from one parent to children. It leads to increased risk of premature heart attacks. Management involves statins and strict dietary changes.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Accelerated atherosclerosis
Dyslipidemia
(cardiovascular)Fatigue or weight changes
(metabolic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Cutaneous xanthomas
(integumentary)Metabolic syndrome features
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
High-Intensity Statin Therapy
HMG-CoA reductase inhibitors as first-line therapy to significantly reduce LDL cholesterol levels and cardiovascular risk in familial hypercholesterolemia.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
LDL-Lowering Diet
Comprehensive heart-healthy diet emphasizing low saturated fat, low cholesterol, high fiber intake with plant sterols/stanols for additional LDL reduction.
Additional treatment options
Ezetimibe Add-On Therapy
Cholesterol absorption inhibitor that reduces intestinal cholesterol absorption, typically added when statin monotherapy is insufficient.
medicationLDL Apheresis
Weekly or biweekly extracorporeal LDL removal for patients with severe FH who fail to reach targets with maximum pharmacotherapy.
procedureCardiovascular Risk Monitoring
Regular assessment of carotid IMT, coronary calcium scoring, and cardiac evaluation to monitor disease progression and guide therapy intensity.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Hypercholesterolemia Autosomal Dominant Type B C1704417?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Hypercholesterolemia Autosomal Dominant Type B C1704417. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy