Hypertriglyceridemia 1 C5444012
A genetic disorder causing high triglyceride levels. It runs in families and can raise heart disease risk. Treatment includes diet, exercise, and sometimes medication.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Recurrent pancreatitis
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Eruptive xanthomas
(integumentary)Lipemia retinalis
(ophthalmic)Hepatosplenomegaly
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Low-Fat and Reduced Sugar Diet
Comprehensive dietary modification limiting saturated fats, trans fats, and refined carbohydrates. This approach directly addresses dietary contributors to elevated triglycerides and supports overall metabolic health.
Regular Physical Exercise
Consistent aerobic exercise regimen of moderate intensity for at least 150 minutes weekly. Physical activity enhances lipoprotein metabolism and can significantly lower triglyceride levels.
Additional treatment options
Lipid-Lowering Pharmacotherapy
Use of triglyceride-lowering medications such as fibrates, omega-3 fatty acids, or statins when lifestyle modifications are insufficient. Medication selection depends on baseline levels and overall cardiovascular risk.
medicationOmega-3 Fatty Acid Supplementation
Supplemental omega-3 fatty acids from fish oil or algae sources to support triglyceride metabolism. Doses should be discussed with a healthcare provider to ensure appropriate intake levels.
complementarySerial Lipid Panel Testing
Regular monitoring of fasting lipid profiles to track triglyceride trends and assess treatment effectiveness. Testing frequency depends on baseline levels and therapeutic interventions.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Hypertriglyceridemia 1 C5444012?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Berglund L, Brunzell JD, Goldberg AC, et al. Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2012;97(9):2969-2989.
Yuan G, Al-Shali KZ, Hegele RA. Hypertriglyceridemia: its etiology, effects and treatment. CMAJ. 2007;176(8):1113-1120.
Lee M, Kim K, Joe HS, et al. Efficacy and safety of fibrates in the management of hypertriglyceridemia: a systematic review and meta-analysis. Atherosclerosis. 2014;232(2):367-378.
Nissen SE, Foundation for the ACC. Impact of icosapent ethyl on triglyceride levels in patients with severe hypertriglyceridemia: the MARINE trial. Circulation. 2016;134(20):1531-1547.
Medication Comparisons
Compare medications used to treat Hypertriglyceridemia 1 C5444012. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy