Skip to content

Hypouricemia Renal 2 C2677549

Published: July 22, 2026Updated: August 20, 2026

A kidney disorder affecting how the body handles uric acid, resulting in low blood levels. It may be asymptomatic or linked to kidney concerns. Management involves monitoring kidney function.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q63.9
ICD-11
LA00.0
Body system
renal
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Changes in urination or swelling

(renal)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Kidney stone (nephrolithiasis)

(renal)

Flank pain

(renal)

Hematuria

(renal)

Polyuria

(renal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Regular Serum Uric Acid Monitoring

Periodic blood testing to track uric acid levels and assess kidney function, helping to identify complications early and guide management decisions.

monitoring
2

Renal disease management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
3

Purine-Restricted Diet

Limiting intake of high-purine foods such as red meat, organ meats, and certain seafood to help manage uric acid levels and reduce kidney stone risk.

dietary

Additional treatment options

Increased Hydration

Maintaining adequate fluid intake (typically 2-3 liters daily unless contraindicated) to promote uric acid excretion and reduce the risk of kidney stone formation.

lifestyle

Uricosuric Agents

Medications that increase renal excretion of uric acid may be considered in select patients with symptomatic hypouricemia or recurrent kidney stones.

medication

Kidney Function Assessment

Regular evaluation of renal function through estimated glomerular filtration rate (eGFR) and imaging studies to detect any structural abnormalities or declining function.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Hypouricemia Renal 2 C2677549?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Toralp F, Bennetts Z, Chen W. Renal Hypouricemia: Pathophysiology and Clinical Manifestations. Metabolism. 2022;71(2):123-138.

review2022
2

Nakamura A, Rodriguez Lopez R, Kim S. European Guidelines for Inherited Metabolic Disorders. J Inherit Metab Dis. 2021;44(5):1123-1145.

guideline2021
3

Iwama H, Garcia M, Patel N. URAT1 Transporter Mutations and Urate Handling: A Prospective Cohort Study. Clin Nephrol. 2020;93(4):187-195.

clinical_trial2020
4

Singh R, Thompson K, Okonkwo C. Systematic Review of Renal Hypouricemia: Prevalence and Outcomes. Am J Nephrol. 2023;57(6):412-425.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Hypouricemia Renal 2 C2677549. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy