Idh Mutant And 1p 19q Codeleted Oligodendroglioma C4288558
A type of brain tumor arising from supportive brain cells, carrying specific genetic markers that guide treatment. It typically affects adults and may cause seizures, headaches, or neurological changes. Treatment often combines surgery, radiation, and chemotherapy with generally favorable outcomes.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Headaches
Focal neurological deficits
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Cognitive decline
(Neurological)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Maximal safe surgical resection
Neurosurgical removal of as much tumor tissue as possible while preserving neurological function. Extent of resection is a critical prognostic factor in oligodendroglioma outcomes.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Chemotherapy for 1p/19q codeleted oligodendroglioma
PCV chemotherapy regimen or temozolomide following surgery and radiation. The 1p/19q codeletion predicts favorable response to chemotherapy in this tumor type.
Additional treatment options
Radiation therapy
Focal radiation therapy to the tumor bed and surrounding margins, typically delivered after surgery and potentially combined with chemotherapy in adjuvant or concurrent protocols.
procedureLong-term tumor surveillance
Regular MRI imaging and clinical monitoring for tumor recurrence or progression, with early detection allowing for timely intervention and treatment modification.
monitoringNeuro-oncology support services
Psychological counseling and cognitive rehabilitation addressing the emotional impact of brain tumor diagnosis and potential treatment-related cognitive changes, including memory and attention difficulties.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Idh Mutant And 1p 19q Codeleted Oligodendroglioma C4288558?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy