Immunodeficiency 132b C6012695
A genetic immunodeficiency disorder affecting immune cell function and increasing susceptibility to infections. Management involves infection prevention, immune support, and regular specialist monitoring.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent respiratory infections
(immunologic)Combined immunodeficiency
(immunologic)Autoimmune cytopenias
(hematologic)Failure to thrive
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Immunoglobulin Replacement Therapy (IVIG)
Regular intravenous or subcutaneous immunoglobulin infusions to provide passive immunity and protect against bacterial and viral infections. This is a cornerstone treatment for antibody deficiencies.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Antimicrobial Prophylaxis
prophylactic antibiotics and antivirals to prevent opportunistic infections common in immunodeficiency. Typically includes TMP-SMX for PCP prevention and antivirals for herpes family viruses.
Additional treatment options
Hematopoietic Stem Cell Transplantation
Curative approach involving replacement of defective immune system with healthy stem cells from a matched donor. Reserved for severe cases not controlled with conventional therapy.
procedureComprehensive Infection Surveillance
Regular monitoring including immunoglobulin levels, infection frequency tracking, and periodic imaging to detect subclinical infections early. Includes vaccination response monitoring.
monitoringImmunonutrition Support
Specialized nutritional support focusing on immune-boosting nutrients including zinc, selenium, vitamin D, and protein adequacy. Enteral nutrition may be needed during illness-related catabolism.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Immunodeficiency 132b C6012695?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy