Immunodeficiency 62 C5193109
A rare inherited immunodeficiency causing the body to lack sufficient immune protection against infections. Usually appears in infancy or early childhood. Treatment focuses on infection prevention and supportive care.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent otitis media
(immunologic)Unexplained fevers
(immunologic)Chronic diarrhea
(immunologic)Growth delay
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Immunoglobulin Replacement Therapy
Intravenous or subcutaneous immunoglobulin replacement provides passive immunity to compensate for the underlying antibody deficiency. Regular infusions help prevent recurrent bacterial infections and reduce infection-related complications.
Antibiotic Prophylaxis
Long-term prophylactic antibiotics help prevent recurrent sinopulmonary infections common in antibody deficiencies. Selection depends on identified pathogens and local resistance patterns.
Additional treatment options
Infection Surveillance Protocol
Regular monitoring with periodic laboratory assessments including immunoglobulin levels, infection frequency tracking, and pulmonary function testing to evaluate disease progression and treatment efficacy.
monitoringHematopoietic Stem Cell Transplant Evaluation
Curative treatment consideration through allogeneic stem cell transplantation for eligible patients with severe immunodeficiency. Requires comprehensive donor matching and pre-transplant infection clearance.
procedureInfection Prevention Practices
Implementation of hygiene measures including hand washing, avoiding crowded indoor spaces during respiratory illness seasons, and prompt medical evaluation for fever to prevent serious complications.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Immunodeficiency 62 C5193109?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy