Immunodeficiency Common Variable 4 C3150739
A disorder of the immune system characterized by poor antibody production. Affected individuals have increased susceptibility to infections and may develop complications.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent pneumonia
(immunologic)Persistent fever
(immunologic)Recurrent cellulitis
(immunologic)Opportunistic fungal infection (candidiasis)
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
IVIG Infusion Therapy
Intravenous immunoglobulin therapy provides exogenous IgG to compensate for deficient antibody production. Dosing is individualized based on weight and trough levels.
Targeted Antimicrobial Therapy
Prompt treatment of detected infections with appropriate antimicrobials prevents complications. Culture-guided therapy is preferred when possible to ensure effectiveness.
Additional treatment options
Pulmonary Rehabilitation
Supervised exercise and breathing programs help maintain lung function and improve exercise tolerance. Particularly beneficial for patients with chronic lung involvement.
physical_therapyPsychological Counseling
Chronic illness counseling addresses anxiety, depression, and coping strategies. Mental health support improves quality of life and treatment adherence.
psychologicalImmunonutrition Support
Specific nutrients including glutamine, probiotics, and antioxidants may support gut-associated immune tissue. A Mediterranean-style diet provides anti-inflammatory benefits.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Immunodeficiency Common Variable 4 C3150739?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Immunodeficiency Common Variable 4 C3150739. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy