Immunodeficiency Common Variable 5 C3150740
A form of immunodeficiency where the body cannot make sufficient protective antibodies. Patients typically need regular immunoglobulin infusions to prevent infections.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent sinopulmonary infections
(immunologic)Autoimmune cytopenias
(immunologic)Chronic diarrhea
(immunologic)Granulomatous skin lesions
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Subcutaneous Immunoglobulin
Home-based subcutaneous infusions offer flexible dosing and steady-state IgG levels. Patients can self-administer after training, improving quality of life and independence.
Azithromycin Prophylaxis
Macrolide antibiotics provide both antimicrobial and immunomodulatory effects. Three-times-weekly dosing reduces respiratory infection frequency in some patients.
Additional treatment options
Pulmonary Function Surveillance
Regular spirometry and imaging detect early bronchiectasis or interstitial lung disease. Early detection allows timely intervention before irreversible damage occurs.
monitoringSteam Inhalation Therapy
Regular steam inhalation with essential oils may support mucociliary clearance and provide symptomatic relief for sinus congestion. Adjunctive to, not replacement for, standard therapy.
complementaryStress Reduction and Sleep Optimization
Stress management through mindfulness and adequate sleep duration supports immune function. Chronic stress impairs immune responses and increases infection susceptibility.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Immunodeficiency Common Variable 5 C3150740?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Immunodeficiency Common Variable 5 C3150740. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy