Immunodeficiency Common Variable 6 C3150741
A condition affecting the immune system's antibody production. It leads to frequent infections and may cause inflammatory complications. Treatment focuses on antibody replacement.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent viral infections
(immunologic)Bronchiectasis
(immunologic)Autoimmune hemolytic anemia
(immunologic)Increased susceptibility to fungal infections
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Immunoglobulin Therapy
Replacement therapy with pooled human immunoglobulin restores humoral immunity. Dosing typically ranges from 400-600 mg/kg every 3-4 weeks for IV administration.
Influenza and Pneumococcal Vaccination
Annual influenza vaccination and pneumococcal immunization reduce infection burden. Patients on immunoglobulin may have attenuated but still beneficial responses.
Additional treatment options
Venous Access Device Placement
For patients requiring frequent IVIG, implanted ports or peripherally inserted central catheters facilitate treatment delivery and reduce venipuncture anxiety.
procedureGastrointestinal Nutritional Management
Patients with GI complications benefit from modified textures and specific carbohydrate diets. Monitoring for malabsorption and microscopic colitis guides dietary interventions.
dietaryAutoimmune Complication Screening
Regular screening for autoimmune manifestations including cytopenias, enteropathy, and granulomatous disease allows early intervention. Annual comprehensive evaluations recommended.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Immunodeficiency Common Variable 6 C3150741?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Immunodeficiency Common Variable 6 C3150741. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy