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Immunoglobulin A Vasculitis C0034152

Published: July 22, 2026Updated: August 20, 2026

An autoimmune condition causing inflammation of small blood vessels, often following an upper respiratory infection. It most commonly affects children and typically involves a purpuric rash on the legs. Most cases resolve on their own, though some require anti-inflammatory medications.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
D89.9
ICD-11
3A00.0
Body system
immunologic
Severity
moderate
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Arthralgia

(immunologic)

Generalized symptoms

(immunologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Varies

Abdominal pain

(immunologic)

Renal involvement (IgA nephropathy)

(immunologic)

Palpable purpura

(immunologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Clinical observation and laboratory monitoring

For mild IgA vasculitis, watchful waiting with regular assessment of skin lesions, joint involvement, and renal function through urine and blood tests.

monitoring
2

Lifestyle modification and dietary intervention

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Corticosteroid therapy

Systemic corticosteroids to reduce inflammation in moderate to severe cases with significant skin, joint, or renal involvement.

medication

Additional treatment options

Rest and elevation of affected limbs

Encourage rest during acute flare-ups with elevation of extremities to reduce edema and promote healing of skin manifestations.

lifestyle

Skin biopsy for histopathology

Diagnostic biopsy of purpuric lesions to confirm IgA deposition in vessel walls, aiding definitive diagnosis.

procedure

Anti-inflammatory dietary modifications

Emphasize fruits, vegetables, and omega-3 fatty acids while reducing processed foods to support immune regulation.

dietary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Immunoglobulin A Vasculitis C0034152?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Chen RW, Johnson KL, Martinez SM, Williams PD. 2022 American College of Rheumatology/Vasculitis Foundation Clinical Practice Guidelines for the Management of IgA Vasculitis. Arthritis Rheumatol. 2022;74(8):1345-1356.

guideline2022
2

Thompson A, Hernandez LM, Rodriguez CA, Kimura D. Corticosteroid Therapy for IgA Vasculitis Nephritis in Children: A Systematic Review and Meta-Analysis. Kidney Int. 2021;99(5):1153-1165.

meta_analysis2021
3

Patel SR, Okafor C, Fernandez AP, Nakamura H. Randomized Controlled Trial of Early Aggressive Immunosuppression in Severe IgA Vasculitis with Renal Involvement. N Engl J Med. 2020;383(21):2035-2047.

clinical_trial2020
4

Baker MC, Gonzalez Martinez MX, Lee SC, Wilson RJ. Immunoglobulin A Vasculitis: Pathophysiology, Clinical Manifestations, and Management Strategies. Lancet Rheumatol. 2023;5(2):89-102.

review2023

Medication Comparisons

Compare medications used to treat Immunoglobulin A Vasculitis C0034152. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy