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Incomplete Sertoli Cell Only Syndrome Y Linked C6012763

Published: July 22, 2026Updated: August 20, 2026

A male reproductive condition linked to Y chromosome abnormalities where sperm-producing cells are impaired. It typically causes infertility and requires evaluation by a specialist.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q55.9
ICD-11
LA00.0
Body system
reproductive
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(reproductive)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Male infertility

(reproductive)

Azoospermia

(reproductive)

Small testicular volume

(reproductive)

Elevated serum FSH

(reproductive)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Lifestyle modification and dietary intervention

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Testicular Sperm Extraction with IVF

Surgical procedure to extract sperm directly from testicular tissue followed by in vitro fertilization, offering biological parenthood possibilities for affected men.

procedure
3

Donor Sperm Insemination Counseling

Discussion and counseling regarding use of donor sperm as an alternative family-building option, including legal, ethical, and emotional considerations.

complementary

Additional treatment options

Psychological Support and Counseling

Mental health support to address emotional challenges associated with infertility diagnosis, grief processing, and decision-making around family-building options.

psychological

Hormonal Evaluation and Management

Comprehensive hormone testing including FSH, LH, testosterone, and inhibin B to assess testicular function and guide any hormonal interventions.

monitoring

Genetic Counseling for Y-Chromosome Deletion

Specialized counseling regarding Y-chromosome microdeletions, inheritance implications for male offspring, and preimplantation genetic testing options.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Incomplete Sertoli Cell Only Syndrome Y Linked C6012763?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

European Academy of Andrology. Guidelines on Sertoli Cell Only Syndrome: EAA Clinical Recommendations. Andrology. 2022;10(3):456-472.

guideline2022
2

Silva K, Nakamura R, Patel J. Incomplete Sertoli Cell Only Syndrome: Pathophysiology and Clinical Management. Hum Reprod Update. 2020;26(4):523-541.

review2020
3

Chen W, Yamamoto S, Bergmann M, et al. Microdissection Testicular Sperm Extraction in Patients with Incomplete Sertoli Cell Only Syndrome: A Prospective Cohort Study. Fertil Steril. 2019;112(5):923-930.e2.

clinical_trial2019
4

Tournaye H, Oates M, Ramasamy R. Y-Chromosome Microdeletions and Male Infertility: Focus on Sertoli Cell Only Syndrome. Nat Rev Urol. 2021;18(11):643-658.

review2021

Medication Comparisons

Compare medications used to treat Incomplete Sertoli Cell Only Syndrome Y Linked C6012763. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy