Intellectual Developmental Disorder Autosomal Recessive 80 With Variant Lissencephaly C5882733
An inherited disorder causing intellectual disability due to incomplete brain development, specifically affecting the brain's surface folds. Both parents must carry the gene for a child to be affected. Treatment focuses on developmental support and symptom management.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Epilepsy
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Severe intellectual disability
(neurologic)Spasticity
(neurologic)Hydrocephalus
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Early Intervention Physical Therapy
Structured physical therapy program focusing on motor development, muscle tone normalization, and prevention of contractures. Therapists work on balance, coordination, and functional mobility appropriate to developmental level.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Cognitive and Behavioral Support Services
Individualized psychological interventions including behavioral therapy, cognitive support strategies, and family counseling to address developmental challenges and improve adaptive functioning.
Additional treatment options
Neurological and Developmental Monitoring
Regular comprehensive assessments of neurological status, developmental progress, seizure activity, and functional abilities to guide treatment adjustments.
monitoringSensory Integration Therapy
Therapeutic approach addressing sensory processing difficulties commonly associated with lissencephaly, helping improve tolerance to sensory stimuli and daily functioning.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Intellectual Developmental Disorder Autosomal Recessive 80 With Variant Lissencephaly C5882733?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy