Intellectual Disability X Linked 46 C1845526
This genetic condition causes intellectual disability from changes on the X chromosome, mainly affecting males. Supportive care including therapy, educational interventions, and family support helps manage the condition.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Behavioral problems
(neurologic)Hypotonia
(neurologic)Agenesis of corpus callosum
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Social Skills Training
Group-based intervention teaching appropriate social behaviors, emotion recognition, and peer interaction skills essential for community integration.
Additional treatment options
Supported Employment Program
Vocational training and job placement assistance with ongoing workplace support designed for individuals with intellectual disabilities.
lifestyleGross Motor Skill Development
Therapeutic activities focused on improving coordination, balance, and physical endurance to enhance mobility and prevent secondary complications.
physical_therapyMulti-Disciplinary Team Review
Regular coordination meetings among healthcare providers, educators, and family to review progress and adjust intervention plans holistically.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Intellectual Disability X Linked 46 C1845526?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Stevenson RE, Schwartz CE, Lubs HA. Clinical guidelines for X-linked intellectual disability syndromes. Am J Med Genet A. 2019.
Moeschler JB, Shevell M, Saul RA. Comprehensive evaluation of intellectual disability: A review. Pediatrics. 2014.
Ropers HH, Hamel BC. X-linked mental retardation: Meta-analysis of genetic factors. Nat Rev Genet. 2015.
Tarquinio DC, Houwink EJ, Van Bokhoven H. Novel therapeutic approaches for X-linked intellectual disability: Clinical trial outcomes. Mol Genet Metab. 2022.
Medication Comparisons
Compare medications used to treat Intellectual Disability X Linked 46 C1845526. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy