Intellectual Disability X Linked Syndromic Houge Type C4538788
X-linked syndromic intellectual disability of Houge type affecting males. Severity varies; supportive therapies include speech, occupational, and behavioral interventions.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Intellectual disability
(neurologic)Developmental delay
(neurologic)Seizures
(neurologic)Growth retardation
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Structured Daily Routine
Implementation of predictable daily schedules with visual supports and clear transitions to reduce anxiety, support learning, and promote independence through consistent environmental organization.
Cognitive Behavioral Approaches
Adapted therapeutic techniques addressing anxiety, emotional regulation, and coping skills using simplified concepts, concrete examples, and repeated practice opportunities.
Additional treatment options
Sensory Integration Therapy
Controlled exposure to sensory experiences and sensory diet activities prescribed by trained therapists to improve sensory processing, reduce sensitivities, and enhance functional engagement.
physical_therapySleep and Circadian Assessment
Evaluation and management of sleep disturbances common in neurodevelopmental syndromes, including sleep hygiene optimization and treatment of underlying sleep disorders.
monitoringNutritional Support Services
Dietitian-guided nutrition planning ensuring adequate caloric and nutrient intake with texture-modified foods if needed and supplementation for identified deficiencies.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Intellectual Disability X Linked Syndromic Houge Type C4538788?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Stevenson RE, Schwartz CE, Raymond GS. Clinical management guidelines for X-linked syndromic intellectual disability disorders. Genet Med. 2021.
Ropers HH, Hamel BC. X-linked intellectual disability: update on genetic subtypes and clinical phenotypes. Nat Rev Genet. 2020.
Mandel H, Zeev HB, Yntema HG. Phenotypic characterization and molecular basis of X-linked syndromic intellectual disability: a prospective cohort study. Am J Hum Genet. 2022.
van der Aa N, Kooy RF, Vandeweyer G. Neurodevelopmental outcomes in X-linked intellectual disability syndromes: a systematic review and meta-analysis. Orphanet J Rare Dis. 2023.
Medication Comparisons
Compare medications used to treat Intellectual Disability X Linked Syndromic Houge Type C4538788. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy