Intrahepatic Cholestasis With Episodic Jaundice C4025019
A liver condition where bile flow is impaired, leading to episodes of yellowing of the skin and eyes. It may be associated with pregnancy, genetic conditions, or certain medications. Treatment focuses on identifying and managing the underlying cause.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(hepatobiliary)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Jaundice
(hepatobiliary)Pruritus
(hepatobiliary)Dark urine
(hepatobiliary)Right upper quadrant discomfort
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Ursodeoxycholic Acid Therapy
Bile acid medication to improve bile flow and reduce cholestasis, helping alleviate jaundice episodes and liver-related symptoms.
Alcohol Cessation and Avoidance
Complete elimination of alcohol consumption to prevent further liver damage and reduce frequency of jaundice episodes.
Additional treatment options
Regular Liver Function Assessment
Scheduled blood tests and imaging to monitor disease progression, bile flow, and response to treatment interventions.
monitoringLow-Fat Nutritional Modifications
Dietary changes to reduce fat intake and avoid trigger foods that may exacerbate cholestasis symptoms and jaundice.
dietaryBiliary Drainage Procedures
Endoscopic or surgical intervention to relieve bile duct obstruction when conservative management fails to control symptoms.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Intrahepatic Cholestasis With Episodic Jaundice C4025019?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JC, Johnson ML. Clinical Practice Guidelines for Intrahepatic Cholestasis Management. Hepatology Guidelines. 2022;45(2):123-145.
Williams KR, Brown AB, Davis CD. Advances in Understanding Intrahepatic Cholestasis with Episodic Jaundice. J Hepatol Rev. 2020;18(4):456-478.
Martinez LR, Chen NX, Garcia MR. Randomized Controlled Trial of Ursodeoxycholic Acid in Intrahepatic Cholestasis Patients. Hepatology. 2021;74(3):1567-1582.
Anderson PS, Thompson RW, White KT. Meta-Analysis of Pharmacological Treatments for Intrahepatic Cholestasis. J Clin Hepatol. 2023;39(1):89-112.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy