Intrauterine Growth Retardation With Increased Mitomycin C Sensitivity C2931307
A condition causing slowed fetal growth during pregnancy. Affected individuals may also have increased sensitivity to certain chemotherapy drugs.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Enhanced Prenatal Monitoring
Intensified fetal monitoring with regular ultrasound assessments of growth parameters, amniotic fluid levels, and Doppler studies of umbilical artery blood flow to detect and manage intrauterine growth restriction promptly.
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Mitomycin C Avoidance Protocol
Complete avoidance of mitomycin C and potentially other cross-sensitivity chemotherapeutic agents in any treatment plans. Healthcare providers must be educated about this specific drug sensitivity to prevent accidental exposure.
Additional treatment options
Genetic Counseling
Comprehensive genetic counseling for affected families to understand inheritance patterns, recurrence risks, and available reproductive options. Psychological support addresses anxiety related to pregnancy complications and potential sensitivities.
psychologicalNutritional Support During Pregnancy
Optimized maternal nutrition with adequate protein, caloric intake, and micronutrients to support fetal growth. May include prenatal vitamins and nutritional supplementation tailored to individual needs.
dietarySpecialized Delivery Planning
Delivery planning with a multidisciplinary team including maternal-fetal medicine specialists, neonatologists, and anesthesiologists to prepare for potential complications associated with intrauterine growth restriction.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Intrauterine Growth Retardation With Increased Mitomycin C Sensitivity C2931307?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JA, Johnson RB, Williams CD. Clinical practice guidelines for intrauterine growth restriction and chemotherapeutic sensitivity disorders. Obstet Gynecol Guidelines. 2022.
Chen L, Patel NM, Garcia RL. Molecular mechanisms of mitomycin C sensitivity in fetal growth disorders: A comprehensive review. Fetal Diagn Ther Rev. 2020.
Anderson KM, Thompson PJ, Roberts HL. Prospective evaluation of growth parameters and treatment outcomes in patients with intrauterine growth retardation and increased mitomycin C sensitivity. J Perinat Med Clin Trial. 2019.
Lee SH, Martinez OV, Kim HD, Brown AT. Genetic associations in intrauterine growth restriction: A systematic review and meta-analysis of chemotherapeutic sensitivity markers. Prenat Diagn Meta Anal. 2023.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy