Jeffries Lakhani Neurodevelopmental Syndrome C5935596
A rare genetic condition affecting brain development, causing intellectual disability and distinctive facial features. Supportive therapies help manage symptoms.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Epilepsy
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Global developmental delay
(neurologic)Intellectual disability
(neurologic)Facial dysmorphism
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Symptom-targeted pharmacotherapy
Pharmacological management addressing specific neurodevelopmental symptoms such as seizures, hyperactivity, or mood dysregulation. Medication selection is individualized based on symptom profile and requires regular reassessment for efficacy and side effects.
Early intervention physical therapy
Structured motor development program targeting gross and fine motor delays through age-appropriate exercises and play-based activities. Therapy focuses on improving coordination, strength, and functional movement patterns.
Additional treatment options
Neuropsychological rehabilitation
Cognitive and behavioral interventions addressing learning difficulties, executive function challenges, and social skills deficits. Includes cognitive remediation strategies and family counseling components.
psychologicalMultidisciplinary developmental monitoring
Regular comprehensive assessments tracking developmental progress across motor, cognitive, and social domains. Involves coordination among neurology, developmental pediatrics, and allied health professionals.
monitoringSensory integration therapy
Structured sensory-based interventions to improve sensory processing and integration, potentially reducing hypersensitivity or hyposensitivity responses. Can include occupational therapy components with environmental modifications.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Jeffries Lakhani Neurodevelopmental Syndrome C5935596?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Jeffries Lakhani Neurodevelopmental Syndrome C5935596. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy