Jejunal Somatostatinoma C1334297
A rare tumor of the jejunum that produces excess somatostatin hormone. Can cause digestive symptoms and other complications. Treatment typically involves surgical removal when possible.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe abdominal pain
Generalized symptoms
(oncologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
New onset diabetes mellitus
(endocrine)Diarrhea (steatorrhea)
(gastrointestinal)Gallbladder disease (cholelithiasis)
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Surgical tumor resection
Complete surgical resection of the somatostatinoma is the primary curative approach when the tumor is localized and resectable, often involving segmental jejunal resection with regional lymph node dissection.
Somatostatin analog therapy
Long-acting somatostatin analogs such as octreotide LAR or lanreotide are used to control hormone hypersecretion symptoms and may slow tumor progression in advanced or metastatic disease.
Additional treatment options
Nutritional support and supplementation
Patients may require nutritional counseling to manage malabsorption, diarrhea, and steatorrhea associated with somatostatinomas, including medium-chain triglyceride supplementation and fat-soluble vitamin replacement.
dietaryRegular surveillance imaging and tumor markers
Ongoing monitoring with CT/MRI imaging every 3-6 months and chromogranin A levels to detect recurrence or metastasis, particularly important for tumors with aggressive features.
monitoringPeptide receptor radionuclide therapy
PRRT with radiolabeled somatostatin analogs may be considered for metastatic well-differentiated neuroendocrine tumors expressing somatostatin receptors, typically after failure of standard therapies.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Jejunal Somatostatinoma C1334297?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Jensen RT, Cadiot G, Brandi ML, et al. ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes. Neuroendocrinology. 2012.
Kulke MH, Shah MH, Benson AB 3rd, et al. Neuroendocrine Tumors, Version 1.2015. J Natl Compr Canc Netw. 2015.
Oberg K, Knigge U, Kwekkeboom D, Perren A. Neuroendocrine Gastro-Entero-Pancreatic Tumors: ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow-up. Ann Oncol. 2012.
Modlin IM, Oberg K, Chung DC, et al. Gastroenteropancreatic Neuroendocrine Tumours. Lancet Oncol. 2008.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy