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Juvenile Amyotrophic Lateral Sclerosis C3468114

Published: July 22, 2026Updated: August 20, 2026

A progressive disease affecting nerve cells that control muscles. It causes increasing weakness, loss of motor function, and eventually breathing difficulties. Treatment involves multidisciplinary supportive care.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
G12.21
ICD-11
8A00.0
Body system
neurologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Respiratory dysfunction

Generalized symptoms

(neurologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Muscle weakness

(musculoskeletal)

Spasticity

(neurologic)

Dysarthria

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Medication management with follow-up

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
2

Riluzole therapy

Riluzole, a glutamate release inhibitor, is the primary disease-modifying medication that may modestly slow disease progression in ALS patients.

medication
3

Muscle strengthening and preservation program

Physical therapy focusing on low-impact exercises to maintain muscle strength, improve circulation, and prevent disuse atrophy while avoiding overexertion.

physical_therapy

Additional treatment options

Symptom management medications

Pharmacological management of muscle cramps, spasticity, excessive salivation, and pseudobulbar affect using targeted agents.

medication

Psychological counseling and support

Mental health support addressing depression, anxiety, and adjustment challenges for both patient and family throughout disease progression.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Juvenile Amyotrophic Lateral Sclerosis C3468114?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Medication Comparisons

Compare medications used to treat Juvenile Amyotrophic Lateral Sclerosis C3468114. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy