Juvenile Hyaline Fibromatosis C2745948
A rare genetic disorder causing firm, noncancerous growths in skin, bone, and other tissues. Treatment involves surgical removal, though growths may recur.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical lesion removal and debulking
Surgical intervention to remove painful, functionally impairing, or cosmetically significant skin nodules and papules characteristic of juvenile hyaline fibromatosis. Procedures may require multiple sessions and careful technique to minimize scarring.
Joint mobility and contracture management
Physical therapy program specifically designed to maintain joint range of motion, prevent worsening contractures, and preserve functional mobility. Includes passive stretching, positioning techniques, and adaptive equipment as needed.
Additional treatment options
Anti-inflammatory and pain management
Pharmacological management of chronic pain and inflammation associated with dermal and soft tissue involvement. May include non-steroidal anti-inflammatory agents and other pain-modifying medications tailored to individual patient response.
medicationPsychosocial support and body image counseling
Psychological support addressing the impact of visible skin lesions, potential disfigurement, and functional limitations on self-esteem and social interaction. Age-appropriate counseling helps children develop coping strategies and resilience.
psychologicalMultisystem disease progression monitoring
Regular assessment of skin lesion burden, joint function, oral involvement, and systemic manifestations including potential bone and visceral involvement. Coordinated care across dermatology, orthopedics, and other specialties.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Juvenile Hyaline Fibromatosis C2745948?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Juvenile Hyaline Fibromatosis C2745948. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy