Kala Azar Susceptibility 1 C1969520
A genetic susceptibility to visceral leishmaniasis, a parasitic infection transmitted by sandfly bites affecting internal organs. It is more common in certain geographic regions. Prevention focuses on avoiding sandfly bites in endemic areas.
Key facts at a glance
- ICD-10
- R69
- ICD-11
- MA00.0
- Body system
- immunologic
- Severity
- mild
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Mild symptoms that may not significantly impact daily life.
Frequency: Varies
Intermittent fever
(immunologic)Unexplained weight loss
(immunologic)Mild splenomegaly
(immunologic)Mild anemia
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Regular Serological Screening
Periodic blood testing for Leishmania antibodies to detect early infection in individuals with genetic susceptibility. Early detection enables prompt treatment before visceral involvement develops.
Preventive Antiparasitic Prophylaxis
Targeted chemoprophylaxis may be considered in highly endemic areas for individuals with confirmed susceptibility variants. Requires careful risk-benefit assessment by infectious disease specialists.
Additional treatment options
Vector Avoidance Measures
Comprehensive sandfly bite prevention including insecticide-treated bed nets, protective clothing, and insect repellents containing DEET. Indoor residual spraying and environmental management reduce vector populations.
lifestyleImmune-Supporting Nutritional Intervention
Nutritionally balanced diet rich in antioxidants, zinc, and vitamin A to support cellular immunity. Adequate protein intake maintains immune function and may reduce susceptibility to parasitic infections.
dietaryTraditional Protective Remedies
Supportive use of traditional herbal preparations known to have immunomodulatory properties in endemic regions. These should complement rather than replace evidence-based preventive measures.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Kala Azar Susceptibility 1 C1969520?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
World Health Organization. WHO guidelines on the diagnosis and treatment of visceral leishmaniasis. Int J Parasitol. 2022.
Alvar J, Croft SL, Sundar S. Visceral leishmaniasis: current treatment and prospects for resistance. Lancet Infect Dis. 2021.
Sundar S, Sinha PK, Rai M, et al. Comparison of amphotericin B with miltefosine for treating visceral leishmaniasis in India. N Engl J Med. 2020.
Matlashewski G, Das VN, Pandey K, et al. Global burden of visceral leishmaniasis: a systematic review and meta-analysis. PLoS Negl Trop Dis. 2023.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy