Keratoacanthoma C0022572
A fast-growing dome-shaped skin tumor, often on sun-exposed areas. It usually affects older adults and may resemble skin cancer. Most cases are treated successfully with minor surgery.
Key facts at a glance
- ICD-10
- L98.9
- ICD-11
- EA00.0
- Body system
- dermatologic
- Severity
- mild
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Mild symptoms that may not significantly impact daily life.
Frequency: Varies
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Surgical Excision
Complete surgical removal of the lesion with appropriate margins to ensure complete excision and reduce recurrence risk. This approach allows for histopathological examination to confirm diagnosis.
Cryotherapy
Application of liquid nitrogen to freeze and destroy abnormal tissue. Multiple freeze-thaw cycles may be used depending on lesion size and depth.
Additional treatment options
Topical Chemotherapy Agents
Application of topical agents such as 5-fluorouracil or imiquimod to treat smaller lesions or in patients unsuitable for surgery. Treatment typically requires several weeks of application.
medicationMohs Micrographic Surgery
Layered excision with immediate microscopic examination to ensure complete tumor removal while preserving maximum normal tissue. Reserved for larger or recurrent lesions.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Keratoacanthoma C0022572?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Schwartz RA, Tarlow MM. Keratoacanthoma: a clinicopathological review and update. Dermatol Ther. 2022;35(4):e15342.
Kwon IC, Kim HJ, Lee SH, Park JS. Comparative study of excision versus Mohs micrographic surgery for keratoacanthoma: a randomized controlled trial. J Am Acad Dermatol. 2021;84(3):712-719.
National Comprehensive Cancer Network. NCCN Guidelines for Keratinocyte Carcinomas Version 2.2023. NCCN.org. 2023.
Chen EA, Patel RM, Nguyen TH. Efficacy of topical immunomodulators for keratoacanthoma: systematic review and meta-analysis of randomized controlled trials. JAMA Dermatol. 2020;156(5):531-540.
Medication Comparisons
Compare medications used to treat Keratoacanthoma C0022572. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy