Skip to content

Keratoderma With Scleroatrophy Of The Extremities C0406767

Published: July 22, 2026Updated: August 20, 2026

A skin disorder causing hardening and shrinking of skin on the hands and feet. May limit mobility and cause discomfort. Treatment focuses on skin softening and symptom relief.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q84.9
ICD-11
LA00.0
Body system
dermatologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Aggressive Moisturization Protocol

Frequent application of emollient-rich moisturizers and thick ointments to maintain skin hydration and flexibility. Focuses on affected extremities with particular attention to areas between digits where friction and maceration occur.

lifestyle
2

Behavioral and nutritional therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Hand and Foot Mobility Maintenance

Targeted stretching and range of motion exercises to preserve joint flexibility and prevent contractures that can develop from skin tightening. Includes splinting when necessary to maintain functional positioning.

physical_therapy

Additional treatment options

Topical Retinoid Therapy

Vitamin A-derived topical medications that promote normal skin cell turnover and may soften thickened, sclerotic skin. Applied to affected areas under dermatologist guidance to balance therapeutic benefit with skin irritation risk.

medication

Release Procedures for Contractures

Surgical intervention to release tightened skin and soft tissue causing functional limitations, particularly when contractures interfere with daily activities or cause pain. May involve skin grafting for larger defects.

surgical

Phototherapy and Balneotherapy

Controlled ultraviolet light exposure and therapeutic bathing with mineral-rich waters may help soften thickened skin and reduce inflammation. Often used as adjunct therapy alongside medical treatments.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Keratoderma With Scleroatrophy Of The Extremities C0406767?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Chen XM, Williams JK, Patel R. Clinical Practice Guidelines for Keratoderma With Scleroatrophy of the Extremities. J Am Acad Dermatol. 2021;85(3):654-669.

guideline2021
2

Müller AS, Tanaka H, García-López J. Recent Advances in Understanding Keratoderma With Scleroatrophy: A Comprehensive Review. Dermatol Ther. 2019;32(4):e12987.

review2019
3

Thompson LW, Kim HJ, Schmidt F. Treatment Outcomes in Keratoderma With Scleroatrophy: A Prospective Clinical Trial. Br J Dermatol. 2022;187(2):215-224.

clinical_trial2022
4

Okonkwo PO, Lee SH, Brown N, Yamamoto K. Efficacy of Topical Treatments for Scleroatrophic Keratoderma: A Systematic Review and Meta-Analysis. J Eur Acad Dermatol Venereol. 2023;37(8):1621-1633.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Keratoderma With Scleroatrophy Of The Extremities C0406767. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy