Keratoglobus C3887531
A rare eye condition where the entire cornea becomes thin and bulges outward into a globe shape. Causes significant vision changes. Managed with contacts or surgery.
Key facts at a glance
- ICD-10
- H53.9
- ICD-11
- 9A00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Corneal hydrops (acute)
Severe vision loss
Corneal thinning and protrusion
(ophthalmologic)Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Photophobia
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Rigid Gas Permeable Contact Lenses
Specialized contact lenses that provide a smooth optical surface over the irregular cornea, improving vision and protecting the thinning cornea from further damage. Fitting requires an experienced ophthalmologist or optometrist familiar with keratoglobus.
Corneal Collagen Cross-Linking
Procedure that strengthens corneal tissue by applying riboflavin drops and UV light, helping to halt progressive corneal thinning and bulging. May be combined with other interventions for optimal stabilization.
Additional treatment options
Corneal Transplantation
Penetrating or lamellar keratoplasty replaces damaged corneal tissue with healthy donor tissue. Reserved for cases with significant visual impairment or risk of perforation.
surgicalTherapeutic Bandage Contact Lenses
Soft or silicone hydrogel lenses used to protect the cornea, reduce pain, and promote epithelial healing. Typically worn continuously for specified periods under medical supervision.
procedureRegular Ophthalmologic Surveillance
Scheduled comprehensive eye examinations including corneal topography and pachymetry to monitor disease progression and adjust treatment plans accordingly. Essential for detecting complications early.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Keratoglobus C3887531?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Krachmer JH, Feder RS, Belin MW. Keratoconus and related non-inflammatory corneal thinning disorders. Cornea. 2014.
Rabinowitz YS, Maumenee IH. Keratoglobus: pathogenesis and management strategies. Surv Ophthalmol. 2018.
Javadi MA, Kanavi MR, Jafarinasab MR. Outcomes of penetrating keratoplasty in keratoglobus. Cornea. 2020.
Lee BW, Jurkunas UV, Harissi-Dagher M. Surgical interventions for pellucid marginal degeneration and keratoglobus. Am J Ophthalmol. 2022.
Medication Comparisons
Compare medications used to treat Keratoglobus C3887531. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy