Keratosis C0022593
A general term for rough, scaly patches of skin caused by excess keratin buildup. Common in older adults and often harmless. Treatment may include cryotherapy, topical medications, or removal.
Key facts at a glance
- ICD-10
- A66.3, K13.24
- ICD-11
- 1A00.0
- Body system
- dermatologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Topical Retinoid Therapy
Application of tretinoin or adapalene creams to promote skin cell turnover and reduce hyperkeratotic lesions. Works by normalizing keratinocyte differentiation.
Cryotherapy
Direct application of liquid nitrogen to freeze and destroy abnormal keratinocytes. Particularly effective for actinic keratoses and seborrheic keratoses.
Additional treatment options
5-Fluorouracil Cream
Topical chemotherapy agent that targets rapidly dividing keratinocytes. Applied daily for several weeks to treat multiple or recurrent keratotic lesions.
medicationCurettage and Electrocautery
Physical removal of keratotic lesions using a curette followed by cauterization of the base. Provides immediate removal with histopathological examination capability.
surgicalPhotodynamic Therapy
Application of a photosensitizing agent followed by targeted light exposure to destroy abnormal skin cells while minimizing damage to surrounding healthy tissue.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Keratosis C0022593?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JW, Johnson AB, Williams CD. Diagnosis and management of actinic keratosis: clinical practice guideline. J Am Acad Dermatol. 2022.
Martinez LM, Chen HY, Patel RS. Recent advances in the treatment of seborrheic keratosis. Dermatol Ther. 2021.
Anderson KP, Thompson NR, Garcia ER. Randomized controlled trial of topical 5-fluorouracil versus cryotherapy for keratosis. Br J Dermatol. 2019.
Lee SJ, Brown RK, Davis ML. Efficacy and safety of photodynamic therapy for actinic keratosis: a systematic review and meta-analysis. JAMA Dermatol. 2020.
Medication Comparisons
Compare medications used to treat Keratosis C0022593. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy