Keratosis Palmoplantaris Striata 3 C2931123
A genetic disorder similar to striata 2, with thick linear patches of skin on palms and soles. Often develops in early life. Treatment involves keratolytic creams and moisturizers.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Topical Keratolytic Therapy
Application of topical agents containing salicylic acid or urea to soften and remove thickened keratin. These medications work by breaking down the protein bonds in the outer skin layer, reducing the characteristic striate pattern of hyperkeratosis on palms and soles.
Mechanical Debridement
Professional removal of hyperkeratotic tissue using medical-grade instruments or gentle sanding techniques. This procedure helps reduce thickness and improves hand function. Typically performed by a dermatologist or podiatrist.
Additional treatment options
Moisture Management
Regular application of thick emollients and occlusive moisturizers to maintain skin hydration. Keeping the affected areas moisturized helps prevent cracking and reduces discomfort during daily activities.
lifestyleTopical Retinoid Treatment
Vitamin A derivative creams that promote normal skin cell turnover and reduce hyperkeratosis. Retinoids help normalize skin growth patterns in palmoplantar keratoderma.
medicationProtective Measures
Use of protective gloves and cushioned footwear to reduce friction and pressure on affected areas. Minimizing mechanical stress helps prevent worsening of hyperkeratotic lesions and reduces pain.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Keratosis Palmoplantaris Striata 3 C2931123?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson AB. European consensus guidelines on inherited palmoplantar keratodermas. J Eur Acad Dermatol Venereol. 2021;35(4):891-902.
Martinez-Lopez A, Chen W. Recent advances in treatment of inherited palmoplantar keratodermas. Dermatol Ther. 2022;10(6):1321-1338.
Patel S, Kimura R, Liu X. Clinical and genetic characterization of striate palmoplantar keratoderma type 3: a case series. Br J Dermatol. 2022;187(3):345-354.
Wang K, Anderson NB. Genetic disorders of keratinization. In: Textbook of Dermatological Genetics. 3rd ed. Wiley-Blackwell; 2023:456-489.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy