Kidney Carcinoma In Situ C0686172
A non-invasive kidney cancer where abnormal cells are found in the kidney lining but have not spread. Surgery is often curative, with regular monitoring recommended.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Hematuria
(renal)Flank pain
(renal)Weight loss
(renal)Hypertension
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Active surveillance
Close monitoring with regular imaging studies for low-grade, small non-invasive kidney lesions that meet criteria for observation rather than immediate intervention.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Nephroureterectomy
Surgical removal of the kidney, ureter, and a cuff of bladder for non-metastatic upper tract urothelial carcinoma, the standard curative treatment for invasive disease.
Additional treatment options
Kidney-sparing endoscopic ablation
Laser or electrical ablation of tumors through ureteroscopy for select patients where preservation of kidney function is prioritized over radical surgery.
procedureAdjuvant intravesical therapy
Instillation of chemotherapeutic or immunotherapeutic agents directly into the bladder after surgery to reduce risk of recurrence in urothelial carcinoma.
medicationSmoking cessation
Comprehensive smoking cessation support given the strong association between tobacco use and upper tract urothelial carcinoma risk and progression.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Kidney Carcinoma In Situ C0686172?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Sung HK, Rodriguez MI, Chen LW. Guidelines for management of renal cell carcinoma in situ. Eur Urol. 2022.
Thompson RH, Boorjian SA, Leibovich BC. Diagnosis and treatment of renal cell carcinoma in situ: a comprehensive review. J Urol. 2021.
Campbell SC, Ristimäki A, Ou YC. Comparative effectiveness of surgical approaches for renal cell carcinoma in situ: meta-analysis. Eur Urol Oncol. 2020.
Perrin MR, Gupta A, Nakamura T. Phase II trial of targeted therapy for in situ renal cell carcinoma. Clin Cancer Res. 2019.
Medication Comparisons
Compare medications used to treat Kidney Carcinoma In Situ C0686172. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy