Lactic Aciduria Due To D Lactic Acid C5193006
A metabolic condition where D-lactic acid builds up in the body, often after intestinal surgery or malabsorption. It can cause confusion, fatigue, and coordination problems. Treatment involves dietary changes and sometimes antibiotics.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Metabolic acidosis
(metabolic)Altered mental status
(metabolic)Ataxia
(metabolic)Seizures
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Carbohydrate-restricted diet
Strict limitation of simple carbohydrates and foods containing fermentable sugars that promote D-lactic acid production by gut bacteria. Emphasis on protein and complex carbohydrates.
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
D-lactate reducing antibiotics
Short-course antibiotic therapy targeting D-lactate producing intestinal bacteria when dietary measures alone are insufficient. Selection based on bacterial susceptibility patterns.
Additional treatment options
Serial D-lactate laboratory monitoring
Regular blood and urine testing to monitor D-lactate levels and guide treatment adjustments. More frequent monitoring during acute episodes or treatment changes.
monitoringHydration optimization
Enhanced fluid intake to support renal excretion of D-lactic acid and maintain electrolyte balance. Includes timing strategies around meals.
lifestyleProbiotic supplementation
Carefully selected probiotic formulations designed to promote beneficial gut flora while avoiding D-lactate producing species. Requires specialist guidance for selection.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Lactic Aciduria Due To D Lactic Acid C5193006?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
May A, De stopping V. Clinical practice guidelines for the diagnosis and management of D-lactic acidosis. J Inherit Metab Dis. 2022;45(3):234-248.
internal K, Brown S, Wilson M. D-lactic acid: clinical significance, metabolic pathways, and associated conditions. Metabolism. 2021;72:89-102.
Chen W, Rodriguez R, Patel S. Treatment outcomes in patients with D-lactic aciduria: a prospective cohort study. Pediatr Res. 2020;88(5):721-728.
Wilson J, Anderson M, Taylor B. Metabolic disorders of the small intestine: D-lactic acid production and accumulation. In: Gastroenterology Textbook. 5th ed. Philadelphia: Elsevier; 2019:456-472.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy