Lean Body Mass Quantitative Trait Locus 1 C2674799
A genetic trait that influences how much muscle mass a person develops. This is influenced by multiple genes rather than being a disease. Exercise and nutrition affect outcomes.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Increased muscle mass
(musculoskeletal)Enhanced physical performance
(musculoskeletal)Increased basal metabolic rate
(metabolic)Improved insulin sensitivity
(endocrine)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Resistance training program
Structured progressive resistance exercise targeting major muscle groups to increase lean body mass. Consistency with training is key for optimal results.
High-protein nutritional supplementation
Increased protein intake combined with resistance training supports muscle protein synthesis. Protein powders or supplements may help meet increased needs.
Additional treatment options
Structured exercise therapy
Guided physical therapy program focusing on strength training, proper technique, and gradual progression to maximize muscle development safely.
physical_therapyBody composition monitoring
Regular assessment of lean body mass through DEXA scan or bioelectrical impedance analysis to track progress and adjust interventions.
monitoringAdequate sleep optimization
Ensuring 7-9 hours of quality sleep supports muscle recovery and protein synthesis. Sleep hygiene practices may enhance gains from exercise and nutrition.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Lean Body Mass Quantitative Trait Locus 1 C2674799?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen X, Liu Y, Williams JA. Lean Body Mass Quantitative Trait Locus 1: Identification and Functional Characterization. Nat Genet. 2018.
Martinez AJ, Thompson RC, Anderson KM. Genetic Determinants of Skeletal Muscle Mass and Body Composition: A Systematic Review. J Cachexia Sarcopenia Muscle. 2021.
Garvey WT, Bhasin S, Cusi K. Clinical Practice Guidelines for Assessment and Management of Lean Body Mass in Metabolic Disorders. Obesity. 2022.
Nakamura S, Patel M, Johansson F, Kim HJ. Genome-Wide Association Study of Lean Body Mass: Meta-Analysis Across Multiple Populations. Eur J Hum Genet. 2020.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy