Leber Congenital Amaurosis 3 C1858677
A genetic eye disorder causing severe vision impairment in infancy. It affects the retina's photoreceptor cells. Treatment involves low vision support and regular eye exams.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe congenital visual impairment
Generalized symptoms
(ophthalmologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Nystagmus
(ophthalmologic)Photophobia
(ophthalmologic)Cataract
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Regular ophthalmologic monitoring
Comprehensive eye examinations including electroretinography, visual field testing, and retinal imaging to track disease progression and detect complications such as cataract or keratoconus. Essential baseline assessment and ongoing evaluation.
Cataract extraction
Surgical removal of cataracts that commonly develop in LCA patients, often combined with intraocular lens implantation when appropriate. Improves remaining functional vision.
Additional treatment options
Early intervention services
Specialized developmental support services including orientation and mobility training, adaptive skills development, and family education to support optimal development despite visual impairment. Addresses sensory integration needs.
psychologicalLow vision rehabilitation
Comprehensive low vision evaluation and training in use of assistive devices, magnification systems, and adaptive technologies to enhance functional abilities for daily activities and education.
complementaryEnvironmental modifications
Home and educational environment adaptations including lighting optimization, contrast enhancement, and safety modifications to support independence and reduce accident risk. Includes guidance on optimal lighting conditions.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Leber Congenital Amaurosis 3 C1858677?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Leber Congenital Amaurosis 3 C1858677. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy