Leber Congenital Amaurosis 5 C1858301
A genetic disorder causing severe vision impairment, typically from birth. It affects the retina's photoreceptor cells. Treatment involves low vision aids and supportive care.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe congenital visual impairment
Generalized symptoms
(ophthalmologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Nystagmus
(ophthalmologic)Photophobia
(ophthalmologic)Optic nerve head drusen
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Regular ophthalmologic monitoring
Comprehensive eye examinations including electroretinography, visual field testing, and retinal imaging to track disease progression. Essential for detecting complications and evaluating any emerging therapeutic options.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Family-centered support services
Comprehensive support addressing emotional, social, and practical needs of patients and families living with congenital blindness. Includes counseling, support groups, and connection to community resources.
Additional treatment options
Low vision rehabilitation program
Comprehensive low vision services including assessment, prescription of optical and electronic aids, and training in their use. Focuses on maximizing remaining vision and developing compensatory strategies.
complementaryKeratoconus management
Treatment of keratoconus when present, which is common in LCA patients. May include corneal cross-linking, intrastromal corneal ring segments, or corneal transplantation depending on severity.
surgicalOrientation and mobility training
Specialized training in spatial orientation, navigation techniques, and safe mobility skills. Includes white cane training, environmental awareness, and use of public transportation and assistive navigation technologies.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Leber Congenital Amaurosis 5 C1858301?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Leber Congenital Amaurosis 5 C1858301. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy