Lipodystrophy Familial Partial Type 8 C5882744
An inherited condition causing selective loss of fat in certain body areas while fat accumulates elsewhere. It affects metabolism and causes insulin resistance. Treatment focuses on managing metabolic complications.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Partial loss of subcutaneous fat (limb and gluteal)
(metabolic)Insulin resistance and type 2 diabetes mellitus
(metabolic)Hypertriglyceridemia
(metabolic)Polycystic ovary syndrome (in females)
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Macronutrient-Balanced Diet
Nutritional approach focusing on controlled carbohydrate intake with emphasis on protein and healthy fats to manage metabolic complications associated with partial fat loss.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Metabolic Pharmacotherapy
Use of insulin sensitisers, lipid-lowering agents, or leptin therapy as indicated by metabolic profile to address insulin resistance, diabetes, and dyslipidemia.
Additional treatment options
Regular Metabolic Assessment
Scheduled evaluations of glycemic control, lipid profiles, liver function, and body composition to track disease progression and treatment efficacy.
monitoringBody Contouring Procedures
Plastic surgery interventions to address abnormal fat distribution patterns, including liposuction of excess fat deposits or reconstructive procedures.
surgicalBody Image Support
Psychological counseling and support addressing the emotional impact of altered body composition, self-esteem issues, and coping strategies for chronic disease management.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Lipodystrophy Familial Partial Type 8 C5882744?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy