Lipoprotein A Elevated Level Of C5394595
An elevated blood fat level that increases risk for heart disease and stroke. Management focuses on diet, exercise, and sometimes medications to reduce cardiovascular risk.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Premature atherosclerosis
Stroke risk
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Coronary artery disease risk
(cardiovascular)Peripheral vascular disease
(vascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cardiovascular Risk Reduction Program
Comprehensive lifestyle modification including smoking cessation, regular aerobic exercise, and weight management to reduce overall cardiovascular risk associated with elevated Lp(a).
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Statin Therapy
Lipid-lowering medications to reduce overall cardiovascular risk and LDL cholesterol levels, though they have limited effect on Lp(a) itself.
Additional treatment options
Cardioprotective Diet
Mediterranean-style or DASH diet emphasizing omega-3 fatty acids, fiber, and plant sterols while limiting saturated fats and refined carbohydrates.
dietaryRegular Cardiovascular Screening
Periodic assessment including carotid ultrasound, coronary calcium scoring, and lipid panel monitoring to detect and quantify atherosclerotic disease burden.
monitoringNiacin Supplementation
Nicotinic acid may modestly reduce Lp(a) levels and improve lipid profile as an adjunct to primary lipid-lowering therapy.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Lipoprotein A Elevated Level Of C5394595?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Mach F, Baigent C, Catapano AL, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Atherosclerosis. 2019.
Kronenberg F, Mora S, Stroes ESG, et al. Lipoprotein(a) in atherosclerotic cardiovascular disease: a scientific statement from the National Lipid Association. J Clin Lipidol. 2020.
Erqou S, Kaptoge S, Thompson A, et al. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA. 2012.
O'Donoghue ML, Fazal S, Reyes AR, et al. Efficacy and safety of tibrisiran in patients with elevated lipoprotein(a): a randomized, placebo-controlled, double-blind, phase 2 trial. Circulation. 2023.
Medication Comparisons
Compare medications used to treat Lipoprotein A Elevated Level Of C5394595. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy