Lissencephaly 7 With Cerebellar Hypoplasia C4225359
A brain malformation affecting both the brain surface and cerebellum. It causes severe developmental delays and movement problems. Treatment focuses on supportive care and managing symptoms.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Severe developmental delay
(neurologic)Cerebellar ataxia
(neurologic)Generalized hypotonia
(neurologic)Dysarthria
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cerebellar symptom management
Pharmacological management of cerebellar symptoms including ataxia and coordination difficulties, often involving medications to improve motor control and reduce associated symptoms.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Vestibular and balance rehabilitation
Specialized therapy targeting balance, coordination, and gait training to address cerebellar hypoplasia-related motor deficits through targeted exercises.
Additional treatment options
Neuroimaging and neurological follow-up
Regular MRI assessments and neurological examinations to monitor cerebellar development and detect any progressive changes requiring intervention adjustment.
monitoringBotulinum toxin injections
Local injections to manage spasticity and dystonia that may accompany cerebellar dysfunction, improving comfort and facilitating therapy.
procedureAdaptive equipment provision
Provision of mobility aids, adaptive seating, and safety equipment to enhance independence and prevent injury during daily activities.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Lissencephaly 7 With Cerebellar Hypoplasia C4225359?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy