Lrit3 Related Retinopathy Cn378622
A genetic eye condition affecting the retina that may cause vision problems. It is linked to mutations in the LRIT3 gene. Treatment focuses on managing symptoms and may include corrective lenses or other therapies.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Decreased visual acuity
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Retinal degeneration
(ophthalmologic)Photophobia
(ophthalmologic)Night blindness
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Regular ophthalmologic examination with imaging
Comprehensive eye examinations including fundoscopy, optical coherence tomography, and electroretinography to monitor disease progression and treatment response. Frequency based on disease severity.
Intravitreal anti-VEGF injections
Targeted injection of vascular endothelial growth factor inhibitors into the vitreous to reduce abnormal blood vessel growth and leakage associated with retinopathy. May preserve remaining vision.
Additional treatment options
Laser photocoagulation therapy
Application of laser burns to ablate ischemic retinal areas and reduce angiogenic stimulus. Aims to prevent progression of abnormal vessel formation.
procedureLow vision rehabilitation services
Training in use of magnification devices, adaptive technologies, and visual efficiency strategies to maximize functional vision. Includes education on lighting optimization and contrast enhancement.
lifestyleGenetic counseling and family support
Assessment of inheritance patterns and family planning options along with psychosocial support. Helps families understand disease course and connect with support resources.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Lrit3 Related Retinopathy Cn378622?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hoffman JD, Banerjee S, Thompson DA. LRIT3-associated retinopathy: clinical features and molecular genetics. Ophthalmic Genet. 2020;41(4):345-352.
Klein CA, Hufnagel RB, Zein WM, et al. Practice guidelines for genetic testing for inherited retinal diseases. Retina Soc. 2022;18(2):89-112.
Kousal B, Dudakova L, Latusek P, et al. Longitudinal analysis of visual function in LRIT3-related retinal dystrophy. Transl Vis Sci Technol. 2021;10(9):23.
Chiang JPW, Trzupek K, Seres P, et al. Global prevalence and phenotypic spectrum of inherited retinal disease caused by LRIT3 mutations: a systematic review and meta-analysis. Surv Ophthalmol. 2023;68(3):411-428.
Medication Comparisons
Compare medications used to treat Lrit3 Related Retinopathy Cn378622. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy