Lynch Syndrome 1 C2936783
An inherited condition that impairs DNA repair, raising risk for colorectal and other cancers. Management focuses on regular screening and preventive care.
Key facts at a glance
- ICD-10
- K30
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Rectal bleeding
Bowel obstruction
Abdominal pain or nausea
(gastrointestinal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Change in bowel habits
(gastrointestinal)Unexplained weight loss
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Intensive colonoscopic surveillance
Regular colonoscopy beginning at age 20-25 or 2-5 years before earliest family cancer diagnosis, repeated every 1-2 years to detect and remove precancerous polyps before malignant transformation.
Aspirin chemoprevention
Regular low-dose aspirin use to reduce colorectal cancer incidence through anti-inflammatory and anti-proliferative effects on the colorectal epithelium, supported by clinical trial evidence.
Additional treatment options
Prophylactic colectomy
Risk-reducing total or partial colectomy for individuals with high mutation penetrance or numerous polyps, eliminating the primary organ at risk for colorectal cancer development.
surgicalEndometrial and ovarian cancer surveillance
Annual endometrial sampling, transvaginal ultrasound, and CA-125 monitoring for women with Lynch syndrome to detect gynecological cancers at early, treatable stages.
medicationLifestyle modification program
Evidence-based lifestyle interventions including smoking cessation, alcohol limitation, maintaining healthy BMI, and regular physical activity to reduce modifiable cancer risk factors.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Lynch Syndrome 1 C2936783?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Lynch Syndrome 1 C2936783. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy