Machado Joseph Disease Type 3 C0751670
A progressive disorder causing coordination difficulties, muscle stiffness, and speech problems. Treatment involves physical therapy and symptom management.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Cerebellar ataxia
(neurologic)Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Ophthalmoplegia
(neurologic)Facial fasciculations
(neurologic)Sleep disturbance
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Intensive Rehabilitation Program
Structured physical therapy emphasizing gait training, vestibular rehabilitation, and strengthening exercises to maintain functional independence.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Dystonia and Spasticity Pharmacotherapy
Botulinum toxin injections for focal dystonia and oral agents for generalized spasticity to improve function and comfort.
Additional treatment options
Deep Brain Stimulation
Surgical implantation of electrodes for stimulation of targets like the thalamus to reduce tremor and dystonia when medications are insufficient.
surgicalAssistive Device Prescription
Provision of appropriate mobility aids such as walkers, wheelchairs, and communication devices to maximize independence and safety.
lifestyleBotulinum Toxin Injections
Targeted injections to treat focal dystonia, spasticity, and sialorrhea that impair function or cause discomfort.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Machado Joseph Disease Type 3 C0751670?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Machado Joseph Disease Type 3 C0751670. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy