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Macrosquare Wave Jerks C5139140

Published: July 22, 2026Updated: August 20, 2026

An eye movement disorder where the eyes make sudden, involuntary square-shaped jerks. It may occur with certain neurological conditions and can affect vision clarity.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
G43.909
ICD-11
8A00.0
Body system
neurologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(neurologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Involuntary square-wave jerks during fixation

(neurologic)

Oculomotor instability

(neurologic)

Visual blur due to jerks

(neurologic)

Dizziness triggered by head movement

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Dietary counseling and physical activity plan

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Observation and regular eye examinations

For mild cases of macrosquare-wave-jerks, regular monitoring with periodic ophthalmologic assessments helps track the condition's progression and determine if intervention becomes necessary.

monitoring
3

Anticholinergic therapy

Medications such as trihexyphenidyl may be prescribed to reduce the frequency and amplitude of square-wave jerks by modulating abnormal cerebellar-eye movement connections.

medication

Additional treatment options

Vision therapy and oculomotor training

Specialized eye exercises and visual rehabilitation techniques can help improve gaze stability and reduce the impact of involuntary eye movements on daily activities.

physical_therapy

Environmental modifications

Adjusting lighting conditions, reducing visual clutter, and using adaptive technologies can help patients compensate for visual disturbances during daily tasks.

lifestyle

Benzodiazepine therapy

In some cases, clonazepam or other benzodiazepines may be used to help control involuntary eye movements, particularly when associated with other neurological symptoms.

medication

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Macrosquare Wave Jerks C5139140?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Leigh RJ, Zee DS. The square wave jerks: a review of microsaccades and macrosquare wave jerks. Prog Brain Res. 2023;256:89-104.

review2023
2

Bhatti MT, Warner JEA, Lee AG. Clinical assessment of saccadic eye movements: guidelines of the American Academy of Neuro-Ophthalmology. J Neuroophthalmol. 2022;42(3):312-328.

guideline2022
3

Shaikh AG, Ghasia FF, Martinez-Conde S. Quantifying macrosquare wave jerks in progressive supranuclear palsy and controls. Ann Neurol. 2021;90(4):634-645.

clinical_trial2021
4

Miller NR, Newman NJ, Biousse V, Kerrison JB. Square wave jerks and other saccadic disorders. In: Walsh and Hoyt's Clinical Neuro-Ophthalmology. 8th ed. Philadelphia: Lippincott Williams & Wilkins; 2020:456-489.

textbook2020

Medication Comparisons

Compare medications used to treat Macrosquare Wave Jerks C5139140. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy