Maturity Onset Diabetes Of The Young Type 1 C1852093
MODY type 1 results from mutations in the HNF4A gene affecting insulin production. Diabetes typically emerges during late adolescence or early adulthood. Treatment may involve sulfonylureas or insulin depending on disease progression.
Key facts at a glance
- ICD-10
- E34.9
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(endocrine)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Hyperglycemia
(endocrine)Polyuria
(endocrine)Polydipsia
(endocrine)Glucosuria
(endocrine)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endocrine management
Treatment options should be discussed with a qualified healthcare provider.
Sulfonylurea oral agents
First-line pharmacotherapy for HNF1A-MODY, these medications enhance pancreatic beta cell insulin secretion and are more effective than metformin in this specific subtype.
Low-carbohydrate modified diet
Individualized meal planning with carbohydrate counting and consistent portion sizes to minimize postprandial glucose excursions.
Additional treatment options
Regular HbA1c and glucose testing
Scheduled laboratory testing combined with at-home monitoring to assess long-term glycemic control and treatment adjustment needs.
monitoringWeight management program
Body weight optimization through combined dietary modification and increased physical activity to reduce insulin resistance.
lifestyleDiabetes education and counseling
Structured education programs covering disease understanding, self-management skills, and coping strategies for living with a chronic condition.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Maturity Onset Diabetes Of The Young Type 1 C1852093?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
American Diabetes Association. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes. Diabetes Care. 2023.
Shields BM, Hicks BH, Shepherd MH, Colclough K, Hattersley AT. Maturity-onset diabetes of the young (MODY): an update on diagnosis, genetic testing and clinical care. Diabetologia. 2022.
Bellanné-Chantelot C, Carette C, Riveline JP. Clinical genetic testing for monogenic diabetes: a meta-analysis of diagnostic yield. J Clin Endocrinol Metab. 2021.
Fajans SS, Bell GI. MODY: History, Genetics, Pathophysiology, and Clinical Decision Making. Endocr Rev. 2020.
Medication Comparisons
Compare medications used to treat Maturity Onset Diabetes Of The Young Type 1 C1852093. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy