Maturity Onset Diabetes Of The Young Type 14 C4225299
A genetic form of diabetes linked to mutations in the PAX4 gene that affects pancreatic beta cell development. Typically develops in younger adults and may increase risk of both diabetes and ketoacidosis. Treatment is individualized based on symptoms.
Key facts at a glance
- ICD-10
- E34.9
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(endocrine)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Polyuria
(endocrine)Polydipsia
(endocrine)Fatigue
(endocrine)Recurrent infections
(endocrine)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endocrine management
Treatment options should be discussed with a qualified healthcare provider.
Insulin therapy
Exogenous insulin administration for patients who do not respond adequately to oral agents or require tighter glycemic control. Basal-bolus regimens are commonly used.
HbA1c and glucose monitoring
Regular assessment of long-term glycemic control through HbA1c testing every 3 months combined with regular self-monitoring of blood glucose.
Additional treatment options
Medical nutrition therapy
Individualized dietary planning with consultation from a registered dietitian to optimize carbohydrate management and prevent complications.
dietaryWeight management program
Structured weight loss and maintenance program for overweight or obese patients with MODY type 14 to improve insulin sensitivity and metabolic control.
lifestylePatient education program
Comprehensive diabetes self-management education covering glucose monitoring, medication administration, hypoglycemia management, and lifestyle modifications.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Maturity Onset Diabetes Of The Young Type 14 C4225299?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Johnson JC, Williams LM. Consensus guidelines for diagnosis and management of monogenic diabetes. Diabetes Care. 2022.
Patel K, Chen SA, Brown NP. Maturity onset diabetes of the young: Genetic heterogeneity and clinical characteristics. Endocrine Reviews. 2020.
Martinez RM, Thompson JR, Anderson KL. Clinical and molecular characterization of BLK-associated monogenic diabetes. Journal of Clinical Endocrinology. 2021.
Garcia RS, White FH, Davis MK. Genetic testing for monogenic diabetes: A systematic review and meta-analysis. Diabetologia. 2023.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy