Meckel Syndrome Type 6 C2676790
A severe inherited disorder affecting multiple organ systems including the brain, kidneys, and limbs. Most affected infants have a very limited lifespan.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- fatal
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Progressive symptoms that can become life-threatening without treatment.
Seek immediate medical attention if symptoms worsen.
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Neonatal intensive monitoring
Continuous vital sign monitoring and comprehensive assessment in a neonatal intensive care setting to identify immediate life-threatening complications such as respiratory distress, renal failure, or sepsis.
Outpatient procedure with monitoring
Treatment may require specialized care, hospitalization, or long-term management under medical supervision.
Encephalocele repair
Surgical intervention to repair neural tube defects and reduce risk of infection, performed by pediatric neurosurgeons after careful evaluation of associated anomalies.
Additional treatment options
Polydactyly correction
Surgical removal of extra digits to improve hand function and prevent complications, typically performed after stabilization of more critical conditions.
surgicalPalliative care and family support
Comprehensive psychosocial support including grief counseling, care coordination, and assistance with decision-making for families navigating complex end-of-life care decisions.
psychologicalGenetic counseling services
Family education about inheritance patterns, recurrence risk assessment, and discussion of reproductive options for future pregnancies.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Meckel Syndrome Type 6 C2676790?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hartmann RJ, Patel SK. Meckel Syndrome Type 6: Genetic Basis and Clinical Manifestations. Orphanet J Rare Dis. 2022.
European Consortium for Rare Developmental Disorders, Nakamura M. Clinical Management of Meckel-Gruber Spectrum Disorders: Consensus Guidelines. Am J Med Genet. 2021.
Chen WH, Okonkwo DO, Fernandez-Lopez A. Renal Dysplasia in Ciliopathies: A Systematic Review and Meta-Analysis. Nephrol Dial Transplant. 2023.
Sato K, Williams N, Bergmann L. Prenatal Diagnosis of Meckel Syndrome Type 6 Using Whole Exome Sequencing: A Prospective Study.Prenat Diagn. 2020.
Medication Comparisons
Compare medications used to treat Meckel Syndrome Type 6 C2676790. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy