Mediastinal Gray Zone Lymphoma C1334657
A rare cancer occurring in the chest area between the lungs. Typically affects adults; treated with chemotherapy and sometimes radiation.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Fever
(oncologic)Night sweats
(oncologic)Weight loss
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
DA-EPOCH chemotherapy regimen
Dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab combination chemotherapy as primary treatment for mediastinal gray zone lymphoma.
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Image-guided biopsy
CT or ultrasound-guided core needle biopsy for definitive histological diagnosis and molecular characterization to guide treatment decisions.
Additional treatment options
Response assessment imaging
Serial PET-CT scans to monitor treatment response and detect residual disease or recurrence following chemotherapy completion.
monitoringResidual mass resection
Surgical removal of residual mediastinal masses following chemotherapy when viable tumor cells are suspected on imaging.
surgicalSupportive care
Nutritional support, infection prevention, and symptom management including pain control and antiemetic therapy during active treatment.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Mediastinal Gray Zone Lymphoma C1334657?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Mediastinal Gray Zone Lymphoma C1334657. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy