Mediastinal Yolk Sac Tumor C1334683
A rare malignant germ cell tumor of the chest, most common in young males. Treated with surgery and chemotherapy, with outcomes depending on tumor stage.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Hemoptysis
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Cough
(oncologic)Gynecomastia
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Complete tumor resection
Aggressive surgical removal of the mediastinal yolk sac tumor when anatomically feasible, aiming for complete resection with negative margins.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
BEP chemotherapy regimen
Bleomycin, etoposide, and cisplatin combination chemotherapy following surgery for metastatic or high-risk disease to prevent recurrence.
Additional treatment options
Tumor marker monitoring
Serial measurements of AFP and other tumor markers to assess treatment response, detect recurrence, and guide therapeutic decisions.
procedureLong-term surveillance imaging
Regular chest CT and MRI scans for early detection of local recurrence or metastatic disease, typically for 5 years post-treatment.
monitoringFertility preservation counseling
Reproductive endocrinology consultation for sperm banking or ovarian tissue preservation prior to chemotherapy in adolescent and adult patients.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Mediastinal Yolk Sac Tumor C1334683?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy