Meier Gorlin Syndrome 4 C3151120
A genetic syndrome affecting growth and skeletal development from birth. Features include underdeveloped ears, patella problems, and short stature. Care focuses on symptom management.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Growth Hormone Therapy
Similar to other Meier-Gorlin subtypes, growth hormone therapy may help address the characteristic short stature. Treatment requires careful endocrine workup and monitoring.
Auricular Reconstruction
Plastic surgical intervention for ear abnormalities including microtia and preauricular tags. May involve staged reconstruction using autologous tissue or prosthetic devices.
Additional treatment options
Musculoskeletal Rehabilitation
Targeted physical therapy program addressing joint laxity, muscle weakness, and mobility limitations common in Meier-Gorlin Syndrome type 4.
physical_therapyComprehensive Periodic Assessment
Scheduled evaluations across multiple specialties including growth monitoring, hearing assessment, orthopedic examination, and dental review to track disease progression and treatment response.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Meier Gorlin Syndrome 4 C3151120?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Biever PM, Nollet F, Kuijpers M. Meier-Gorlin Syndrome: Clinical Features and Molecular Basis. Orphanet J Rare Dis. 2020.
Hawthorne K, Veltman JA, de Munnik SA. Pathogenic Variants in ORC1 and Meier-Gorlin Syndrome Phenotype Expansion. Am J Med Genet A. 2019.
Sato K, Yamaguchi T, Abe H. Clinical Heterogeneity in Meier-Gorlin Syndrome: Report of Three Novel Cases. Clin Dysmorphol. 2018.
Thompson E, H anchard N, Klopstock T. European Consensus Statement on Diagnosis and Management of Rare Genetic Skeletal Disorders. Eur J Hum Genet. 2022.
Medication Comparisons
Compare medications used to treat Meier Gorlin Syndrome 4 C3151120. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy