Menarche Age At Quantitative Trait Locus 2 C2752070
A genetic region associated with the timing of first menstruation. Like other genetic factors, it runs in families and affects puberty onset.
Key facts at a glance
- ICD-10
- Q55.9
- ICD-11
- LA00.0
- Body system
- reproductive
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Early menarche
(reproductive)Generalized symptoms
(reproductive)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Delayed menarche
(reproductive)Irregular menstrual cycles
(reproductive)Secondary amenorrhea
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endocrine evaluation
Comprehensive hormonal assessment including FSH, LH, estrogen, and thyroid function tests to evaluate for underlying endocrine disorders affecting menarche timing.
Healthy lifestyle changes and stress management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Additional treatment options
Nutritional optimization
Ensuring adequate intake of essential nutrients including iron, vitamin D, calcium, and healthy fats that support normal pubertal development and reproductive health.
dietaryPsychological counseling
Supportive counseling to address anxiety, stress, or body image concerns related to menarche timing, particularly if significantly delayed or early compared to peers.
psychologicalPelvic ultrasound
Non-invasive imaging to assess uterine and ovarian development, rule out anatomical abnormalities, and evaluate endometrial thickness in cases of delayed menarche.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Menarche Age At Quantitative Trait Locus 2 C2752070?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Elks CE, Perry JR, Sulem P, et al. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet. 2010;42(12):1077-1085.
Day FR, Elks CE, Murray A, et al. Puberty timing associated with type 2 diabetes and obesity in women: findings from the UK Biobank. J Clin Endocrinol Metab. 2015;100(9):3287-3296.
Morris DH, Jones ME, Schoemaker MJ, et al. Body mass index, exercise, and other lifestyle factors in relation to age at menarche: analysis of the Breakthrough Generations Study. Int J Obes (Lond). 2012;36(4):597-604.
Parent AS, Teilmann G, Juul A, et al. The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration. Endocr Rev. 2003;24(5):668-693.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy