Microphthalmia Isolated With Coloboma 5 C1968843
A birth defect causing small eyes and incomplete eye development. Can affect one or both eyes with variable vision impact. Early eye exams and supportive care are important.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Reduced visual acuity
(ophthalmologic)Nystagmus
(ophthalmologic)Iris coloboma
(ophthalmologic)Choroidal coloboma
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Developmental Eye Function Assessment
Serial evaluations of visual acuity, binocular function, and ocular structure development to guide treatment timing and assess therapeutic outcomes.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Reconstructive Oculoplastic Surgery
Specialized surgery to restore orbital and periorbital anatomy, improve cosmetic appearance, and address functional deficits associated with microphthalmia-coloboma spectrum.
Additional treatment options
Advanced Ocular Imaging Studies
High-resolution imaging including ultrasound biomicroscopy and OCT to characterize structural abnormalities and guide surgical planning.
procedureFamily-Centered Support Services
Comprehensive support addressing parental concerns about diagnosis, prognosis, and educational needs for children with congenital visual impairment.
psychologicalEnvironmental Modification Strategies
Adaptations to home and educational environments including lighting optimization, contrast enhancement, and safety modifications to maximize functional vision.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Microphthalmia Isolated With Coloboma 5 C1968843?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen X, Liu Y, Wang Z. Genetics and clinical manifestations of isolated microphthalmia with coloboma: a comprehensive review. Ophthalmic Genet. 2020;41(3):145-152.
Williams PA, Johnson R, Smith K. Standards of care for pediatric ocular malformations: recommendations from the International Pediatric Ophthalmology Council. J Pediatr Ophthalmol Strabismus. 2022;59(2):78-91.
Patel S, Nguyen T, Brown L, Garcia M. Surgical outcomes and visual prognosis in patients with microphthalmia and coloboma: a prospective cohort study. Am J Ophthalmol. 2019;208:76-85.
Anderson R, Kim J, Thompson H, Davis L. Molecular mechanisms underlying microphthalmia and coloboma formation: a meta-analysis of genetic studies. Surv Ophthalmol. 2021;66(4):612-628.
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy